Mode of inhibitory binding of epigallocatechin gallate to the ubiquitin-activating enzyme Uba1 via accelerated molecular dynamics
The green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) and some of its analogs potently inhibit the ubiquitin-activating enzyme Uba1. In an effort to understand the possible molecular basis of inhibitory activity of EGCG, we conducted a molecular docking and molecular dynamics simulation stu...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2021
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| Sorozat: | RSC ADVANCES
11 No. 14 |
| Tárgyszavak: | |
| doi: | 10.1039/d0ra09847g |
| mtmt: | 31951832 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/24740 |