Rationally designed foldameric adjuvants enhance antibiotic efficacy via promoting membrane hyperpolarization
The negative membrane potential of bacterial cells influences crucial cellular processes. Inspired by the molecular scaffold of the antimicrobial peptide PGLa, we have developed antimicrobial foldamers with a computer-guided design strategy. The novel PGLa analogues induce sustained membrane hyperpo...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2022
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| Sorozat: | MOLECULAR SYSTEMS DESIGN & ENGINEERING
7 No. 1 |
| Tárgyszavak: | |
| doi: | 10.1039/D1ME00118C |
| mtmt: | 32493048 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/24074 |