Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression

Splice variants of CD74 differentially modulate the activity of cathepsin L (CTSL). As CD74 and CTSL participate in the pathogenesis of inflammatory diseases such as rheumatoid arthritis (RA), we determined whether splice variants of CD74 could be biomarkers of disease activity. Gene expression was...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Clanchy Felix I. L.
Borghese Federica
Bystrom Jonas
Balog Attila
Penn Henry
Taylor Peter C.
Stone Trevor W.
Mageed Rizgar A.
Williams Richard O.
Dokumentumtípus: Cikk
Megjelent: 2022
Sorozat:JOURNAL OF AUTOIMMUNITY 128
Tárgyszavak:
doi:10.1016/j.jaut.2022.102810

mtmt:32741207
Online Access:http://publicatio.bibl.u-szeged.hu/23857

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