The effect of endometrial thickness on IVF/ICSI outcome

Background: During the menstrual cycle the endometrium undergoes cyclic proliferative and secretory changes in preparation for implantation. If this preparation is not sufficient, then implantation will fail. The impact of endometrial thickness on the day of embryo transfer on IVF outcome was invest...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kovács Péter Tamás
Matyas Sz
Boda Krisztina
Kaali S. G.
Dokumentumtípus: Cikk
Megjelent: 2003
Sorozat:HUMAN REPRODUCTION 18 No. 11
Tárgyszavak:
doi:10.1093/humrep/deg461

mtmt:1679420
Online Access:http://publicatio.bibl.u-szeged.hu/23511
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024 7 |a 10.1093/humrep/deg461  |2 doi 
024 7 |a 1679420  |2 mtmt 
040 |a SZTE Publicatio Repozitórium  |b hun 
041 |a Angol 
100 1 |a Kovács Péter Tamás 
245 1 4 |a The effect of endometrial thickness on IVF/ICSI outcome  |h [elektronikus dokumentum] /  |c  Kovács Péter Tamás 
260 |c 2003 
300 |a 2337-2341 
490 0 |a HUMAN REPRODUCTION  |v 18 No. 11 
520 3 |a Background: During the menstrual cycle the endometrium undergoes cyclic proliferative and secretory changes in preparation for implantation. If this preparation is not sufficient, then implantation will fail. The impact of endometrial thickness on the day of embryo transfer on IVF outcome was investigated in the present study. Methods: A retrospective analysis was conducted of 1228 IVF/ICSI cycles. Stimulation was with clomiphene citrate (CC) + hMG in one-third of the cycles, and ultrashort GnRH agonist stimulation in two-thirds. Cycle parameters were compared between pregnant and non-pregnant patients. A similar comparison was made between ongoing pregnancies and those that resulted in a loss. Results: There were more follicles, oocytes and embryos, the endometrium was thicker and the embryo quality was higher among women who became pregnant when compared with non-pregnant women after assisted reproduction. The pregnancy rate improved as endometrial thickness increased. No difference in cycle parameters and endometrial thickness was found between ongoing pregnancies and pregnancies that resulted in a first-trimester loss. CC had no measurable adverse endometrial effect, but the pregnancy rate was lower in CC+hMG cycles. Conclusions: Increased endometrial thickness is associated with higher pregnancy rates. However, neither attainment of pregnancy nor pregnancy outcome was predicted by endometrial thickness alone. 
650 4 |a Biológiai tudományok 
650 4 |a Klinikai orvostan 
650 4 |a Egészségtudományok 
700 0 1 |a Matyas Sz.  |e aut 
700 0 1 |a Boda Krisztina  |e aut 
700 0 1 |a Kaali S. G.  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/23511/1/Kovacs1.pdf  |z Dokumentum-elérés