Synthesis and Fluorescence Mechanism of the Aminoimidazolone Analogues of the Green Fluorescent Protein Towards Advanced Dyes with Enhanced Stokes Shift, Quantum Yield and Two-Photon Absorption /
Novel small-molecular analogues the green fluorescence protein (GFP) chromophore are synthesised to expand and improve this fluorophore family and to deepen the understanding of their fluorescence mechanism. The introduction of an aminophenyl substituent and the repositioning of the hydroxyl group t...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2021
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| Sorozat: | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
2021 No. 41 |
| Tárgyszavak: | |
| doi: | 10.1002/ejoc.202101173 |
| mtmt: | 32399352 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/23508 |
| LEADER | 02194nab a2200301 i 4500 | ||
|---|---|---|---|
| 001 | publ23508 | ||
| 005 | 20220208083328.0 | ||
| 008 | 220208s2021 hu o 0|| Angol d | ||
| 022 | |a 1434-193X | ||
| 024 | 7 | |a 10.1002/ejoc.202101173 |2 doi | |
| 024 | 7 | |a 32399352 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a Angol | ||
| 100 | 1 | |a Kovács Ervin | |
| 245 | 1 | 0 | |a Synthesis and Fluorescence Mechanism of the Aminoimidazolone Analogues of the Green Fluorescent Protein |h [elektronikus dokumentum] : |b Towards Advanced Dyes with Enhanced Stokes Shift, Quantum Yield and Two-Photon Absorption / |c Kovács Ervin |
| 260 | |c 2021 | ||
| 300 | |a 5649-5660 | ||
| 490 | 0 | |a EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |v 2021 No. 41 | |
| 520 | 3 | |a Novel small-molecular analogues the green fluorescence protein (GFP) chromophore are synthesised to expand and improve this fluorophore family and to deepen the understanding of their fluorescence mechanism. The introduction of an aminophenyl substituent and the repositioning of the hydroxyl group to enable strong intramolecular hydrogen bonding, not only enhances fluorescence emission, but also results in an increased Stokes shift and a considerable red shift. Experimental and computational results describe a dual fluorescence involving both excited-state intramolecular proton transfer and internal charge transfer (ESIPT?ICT) mechanism. The further improvement of the photophysical properties via the systematic variation of dialkylamino substituents at a single position of the chromophore led to a two-orders of magnitude enhancement in the quantum yields. In addition, the novel compounds also have significant two-photon absorption, which widens the possibilities for applications in the field of bioimaging. | |
| 650 | 4 | |a Kémiai tudományok | |
| 700 | 0 | 1 | |a Cseri Levente |e aut |
| 700 | 0 | 1 | |a Jancsó Attila |e aut |
| 700 | 0 | 1 | |a Terényi Ferenc |e aut |
| 700 | 0 | 1 | |a Fülöp Anna |e aut |
| 700 | 0 | 2 | |a Rózsa J. Balázs |e aut |
| 700 | 0 | 2 | |a Galbács Gábor |e aut |
| 700 | 0 | 2 | |a Mucsi Zoltán |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/23508/1/SynthesisandFluorescenceMechanismoftheAminoimidazoloneAnaloguesofEJOC2021.pdf |z Dokumentum-elérés |