Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures
Objective Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to be involved in the generation of absence seizures (ASs), and there is evidence that cortical and thalamic HCN channel dysfunctions may have a proabsence role. Many HCN channel blockers are available, but their...
Elmentve itt :
Szerzők: |
Iacone Yasmine Morais Tatiana P. David Francois Delicata Francis Sandle Joanna Raffai Tímea Parri Harri Rheinallt Weisser Johan Juhl Bundgaard Christoffer Klewe Ib Vestergaard Tamás Gábor Thomsen Morten Skøtt Crunelli Vincenzo Lőrincz László Magor |
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Dokumentumtípus: | Cikk |
Megjelent: |
2021
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Sorozat: | EPILEPSIA
62 No. 7 |
Tárgyszavak: | |
doi: | 10.1111/epi.16926 |
mtmt: | 32037613 |
Online Access: | http://publicatio.bibl.u-szeged.hu/23324 |
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