Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures

Objective Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to be involved in the generation of absence seizures (ASs), and there is evidence that cortical and thalamic HCN channel dysfunctions may have a proabsence role. Many HCN channel blockers are available, but their...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Iacone Yasmine
Morais Tatiana P.
David Francois
Delicata Francis
Sandle Joanna
Raffai Tímea
Parri Harri Rheinallt
Weisser Johan Juhl
Bundgaard Christoffer
Klewe Ib Vestergaard
Tamás Gábor
Thomsen Morten Skøtt
Crunelli Vincenzo
Lőrincz László Magor
Dokumentumtípus: Cikk
Megjelent: 2021
Sorozat:EPILEPSIA 62 No. 7
Tárgyszavak:
doi:10.1111/epi.16926

mtmt:32037613
Online Access:http://publicatio.bibl.u-szeged.hu/23324

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