A three-component reagent system for rapid and mild removal of O-, N- and S-trityl protecting groups
A new reagent system consisting of a Lewis acid such as BF3·Et2O or Cu(OTf)2, the mild protic acid hexafluoroisopropanol and the reducing quenching agent triethylsilane was elaborated for O-, N- and S-detritylation of nucleoside, carbohydrate and amino acid derivatives. The method is compatible with...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2016
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| Sorozat: | ORGANIC & BIOMOLECULAR CHEMISTRY
14 No. 12 |
| Tárgyszavak: | |
| doi: | 10.1039/C6OB00067C |
| mtmt: | 3017583 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/22729 |