Carboxylated magnetic nanoparticles as MRI contrast agents Relaxation measurements at different field strengths /

At the moment the biomedical applications of magnetic fluids are the subject of intensive scientific interest. In the present work, magnetite nanoparticles (MNPs) were synthesized and stabilized in aqueous medium with different carboxylic compounds (citric acid (CA), polyacrylic acid (PAA), and sodi...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Jedlovszky-Hajdú Angéla
Csákiné Tombácz Etelka
Bányai István
Babos Magor
Palkó András
Dokumentumtípus: Cikk
Megjelent: 2012
Sorozat:JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS 324 No. 19
Tárgyszavak:
doi:10.1016/j.jmmm.2012.05.031

mtmt:2001067
Online Access:http://publicatio.bibl.u-szeged.hu/22629
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520 3 |a At the moment the biomedical applications of magnetic fluids are the subject of intensive scientific interest. In the present work, magnetite nanoparticles (MNPs) were synthesized and stabilized in aqueous medium with different carboxylic compounds (citric acid (CA), polyacrylic acid (PAA), and sodium oleate (NaOA)), in order to prepare well stabilized magnetic fluids (MFs). The magnetic nanoparticles can be used in the magnetic resonance imaging (MRI) as contrast agents. Magnetic resonance relaxation measurements of the above MFs were performed at different field strengths (i.e., 0.47, 1.5 and 9.4 T) to reveal the field strength dependence of their magnetic responses, and to compare them with that of ferucarbotran, a well-known superparamagnetic contrast agent. The measurements showed characteristic differences between the tested magnetic fluids stabilized by carboxylic compounds and ferucarbotran. It is worthy of note that our magnetic fluids have the highest r2 relaxivities at the field strength of 1.5 T, where the most of the MRI works in worldwide. 
650 4 |a Fizikai tudományok 
650 4 |a Klinikai orvostan 
700 0 2 |a Csákiné Tombácz Etelka  |e aut 
700 0 2 |a Bányai István  |e aut 
700 0 2 |a Babos Magor  |e aut 
700 0 2 |a Palkó András  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/22629/1/20010671-s2.0-S0304885312004374-main.pdf  |z Dokumentum-elérés