Alzheimer risk factors age and female sex induce cortical Aβ aggregation by raising extracellular zinc
Aging and female sex are the major risk factors for Alzheimer's disease and its associated brain amyloid-beta (A beta) neuropathology, but the mechanisms mediating these risk factors remain uncertain. Evidence indicates that A beta aggregation by Zn(2+)released from glutamatergic neurons contri...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2020
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| Sorozat: | MOLECULAR PSYCHIATRY
25 No. 11 |
| doi: | 10.1038/s41380-020-0800-y |
| mtmt: | 31341681 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/19322 |