Prevalence, Presentation and Treatment of 'Balloon Undilatable' Chronic Total Occlusions Insights from a Multicenter US Registry /

BACKGROUND: The prevalence, treatment and outcomes of balloon undilatable chronic total occlusions (CTOs) have received limited study. METHODS: We examined the prevalence, clinical and angiographic characteristics, and procedural outcomes of percutaneous coronary interventions (PCIs) for balloon und...

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Elmentve itt :
Bibliográfiai részletek
Szerzők: Tajti Péter
Karmpaliotis Dimitri
Alaswad Khaldoon
Toma Catalin
Choi James W.
Jaffer Farouc A.
Doing Anthony H.
Patel Mitul
Mahmud Ehtisham
Uretsky Barry
Karatasakis Aris
Karácsonyi Judit
Danek Barbara A.
Rangan Bavana V.
Ungi Imre
Dokumentumtípus: Cikk
Megjelent: 2018
Sorozat:CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 91 No. 4
doi:10.1002/ccd.27510

mtmt:3337061
Online Access:http://publicatio.bibl.u-szeged.hu/16895
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245 1 0 |a Prevalence, Presentation and Treatment of 'Balloon Undilatable' Chronic Total Occlusions  |h [elektronikus dokumentum] :  |b Insights from a Multicenter US Registry /  |c  Tajti Péter 
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490 0 |a CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS  |v 91 No. 4 
520 3 |a BACKGROUND: The prevalence, treatment and outcomes of balloon undilatable chronic total occlusions (CTOs) have received limited study. METHODS: We examined the prevalence, clinical and angiographic characteristics, and procedural outcomes of percutaneous coronary interventions (PCIs) for balloon undilatable CTOs in a contemporary multicenter US registry. RESULTS: Between 2012 and 2017 data on balloon undilatable lesions were available for 425 consecutive CTO PCIs in 415 patients in whom guidewire crossing was successful: 52 of 425 CTOs were balloon undilatable (12%). Mean patient age was 65 +/- 10 years and most patients were men (84%). Patients with balloon undilatable CTOs were more likely to be diabetic (67 vs. 41%, P < 0.001) and have heart failure (44 vs. 28%, P = 0.027). Balloon undilatable CTOs were longer (40 mm [interquartile range, IQR 20-50] vs. 30 [IQR 15-40], P = 0.016), more likely to have moderate/severe calcification (87 vs. 54%, P < 0.001), and had higher J-CTO score (3.2 +/- 1.1 vs. 2.5 +/- 1.3, P < 0.001) and PROGRESS-CTO complications score (3.9 +/- 1.7 vs. 3.1 +/- 2.0, P < 0.005). They were associated with lower technical and procedural success (92 vs. 98%, P = 0.024; and 88 vs. 96%, P = 0.034, respectively) and higher risk for in-hospital major adverse events (8 vs. 2%, P = 0.008) due to higher perforation rates. The most frequent treatments for balloon undilatable CTOs were high pressure balloon inflations (64%), rotational atherectomy (31%), laser (21%), and cutting balloons (15%). CONCLUSIONS: Balloon undilatable CTOs are common and are associated with lower success and higher complication rates. CLINICAL TRIAL REGISTRATION: NCT02061436, Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO). 
700 0 1 |a Karmpaliotis Dimitri  |e aut 
700 0 1 |a Alaswad Khaldoon  |e aut 
700 0 1 |a Toma Catalin  |e aut 
700 0 1 |a Choi James W.  |e aut 
700 0 1 |a Jaffer Farouc A.  |e aut 
700 0 1 |a Doing Anthony H.  |e aut 
700 0 1 |a Patel Mitul  |e aut 
700 0 1 |a Mahmud Ehtisham  |e aut 
700 0 1 |a Uretsky Barry  |e aut 
700 0 1 |a Karatasakis Aris  |e aut 
700 0 1 |a Karácsonyi Judit  |e aut 
700 0 1 |a Danek Barbara A.  |e aut 
700 0 1 |a Rangan Bavana V.  |e aut 
700 0 1 |a Ungi Imre  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/16895/1/2018_Prevalence_presentation-Catheterization_and_Cardiovascular_Interventions.pdf  |z Dokumentum-elérés