Comparison of the efficiency of Na+/Ca2+ exchanger or Na+/H+ exchanger inhibition and their combination in reducing coronary reperfusion-induced arrhythmias
During ischaemia/reperfusion, the rise in [Na+]i, induced by simultaneous depression of the Na+/K+-ATPase and activation of the Na+/H+ exchanger (NHE), shifts the Na+/Ca2+ exchanger (NCX) into reverse transport mode, resulting in Ca2+ i overload, which is a critical factor in enhancing the liability...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2015
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| Sorozat: | JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
66 No. 2 |
| mtmt: | 2884931 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/15063 |