Left atrial volumetric and strain analysis by three-dimensional speckle-tracking echocardiography in noncompaction cardiomyopathy results from the MAGYAR-path study /

Introduction: Noncompaction cardiomyopathy (NCCM) is a rare congenital cardiomyopathy characterised by a distinctive 2-layered appearance of the myocardium due to hypertrabecularisation and deep intertrabecular recesses. The present study was designed to assess left atrial (LA) volumes and volumetri...

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Bibliographic Details
Main Authors: Nemes Attila
Piros Györgyike Ágnes
Domsik Péter
Kalapos Anita
Forster Tamás
Format: Article
Published: 2016
Series:HELLENIC JOURNAL OF CARDIOLOGY 57 No. 1
doi:10.1016/S1109-9666(16)30014-8

mtmt:3115732
Online Access:http://publicatio.bibl.u-szeged.hu/13648
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Summary:Introduction: Noncompaction cardiomyopathy (NCCM) is a rare congenital cardiomyopathy characterised by a distinctive 2-layered appearance of the myocardium due to hypertrabecularisation and deep intertrabecular recesses. The present study was designed to assess left atrial (LA) volumes and volumetric and strainbased functional properties by three-dimensional speckle-tracking echocardiography (3DSTE) in NCCM. Methods: The study included 12 consecutive NCCM patients. Their results were compared to 20 age-and sex-matched healthy controls. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all cases. Results: Calculated LA maximum (76.5 ± 26.8 mL vs. 45.3 ± 15.1 mL, p=0.0002) and minimum (56.9 ± 27.3 mL vs. 25.3 ± 15.2 mL, p=0.0002) volumes and LA volume before atrial contraction (67.1 ± 28.2 mL vs. 35.7 ± 16.4 mL, p=0.0004) were significantly greater in NCCM patients. Total, active, and passive LA emptying fractions proved to be smaller in NCCM. Peak global radial (-9.3 ± 7.8% vs.-16.8 ± 10.2%, p=0.05), circumferential (12.8 ± 8.4% vs. 26.2 ± 9.2%, p=0.0003), longitudinal (12.8 ± 8.2% vs. 22.5 ± 8.5%, p=0.004), and area (26.7 ± 18.5% vs. 51.6 ± 20.3%, p=0.001) strains were significantly smaller in NCCM patients as compared to matched controls. Conclusions: Significantly greater LA volumes and compromised LA functional properties could be demonstrated by 3DSTE in patients with NCCM. © 2016, Hellenic Cardiological Society. All rights reserved.
Physical Description:23-29
ISSN:1109-9666