Aortic stiffness is increased in patients with hypereosinophilic syndrome being in early necrotic phase

Background: Persistent eosinophilia and eosinophil-mediated single- or multiple-organ damage are typical features of hypereosinophilic syndrome (HES). Theoretically, eosinophilic infiltration of the ascending aortic wall could not be excluded in HES, therefore the present study aimed to test whether...

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Elmentve itt :
Bibliográfiai részletek
Szerzők: Nemes Attila
Marton Imelda
Domsik Péter
Kalapos Anita
Pósfai Éva
Modok Szabolcs
Borbényi Zita
Forster Tamás
Dokumentumtípus: Cikk
Megjelent: AME Publishing Company 2017
Sorozat:QUANTITATIVE IMAGING IN MEDICINE AND SURGERY 7 No. 6
doi:10.21037/qims.2017.12.06

mtmt:3347578
Online Access:http://publicatio.bibl.u-szeged.hu/13641
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245 1 0 |a Aortic stiffness is increased in patients with hypereosinophilic syndrome being in early necrotic phase  |h [elektronikus dokumentum] /  |c  Nemes Attila 
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490 0 |a QUANTITATIVE IMAGING IN MEDICINE AND SURGERY  |v 7 No. 6 
520 3 |a Background: Persistent eosinophilia and eosinophil-mediated single- or multiple-organ damage are typical features of hypereosinophilic syndrome (HES). Theoretically, eosinophilic infiltration of the ascending aortic wall could not be excluded in HES, therefore the present study aimed to test whether HES is associated with abnormalities in aortic elastic properties. Methods: The present study comprised 10 HES patients (mean age: 57.6+/-10.1 years, 5 males) without known cardiovascular disease, their results were compared to 19 age-, gender- and risk factor-matched controls (59.2+/-4.2 years, 15 males). Complete two-dimensional Doppler echocardiography with measurement of echocardiographic aortic elastic properties was performed in all HES cases and controls. Results: Although neither systolic (30.6+/-3.4 vs. 30.1+/-3.6 mm, P=ns), nor diastolic (28.7+/-3.6 vs. 27.8+/-3.2 mm, P=ns) aortic diameter differed significantly between HES patients and matched controls, significantly increased aortic stiffness index (11.19+/-5.65 vs. 7.04+/-2.97, P<0.05) could be demonstrated in HES patients. Conclusions: Increased aortic stiffness could be demonstrated in HES patients in their early necrotic phase. 
700 0 1 |a Marton Imelda  |e aut 
700 0 1 |a Domsik Péter  |e aut 
700 0 1 |a Kalapos Anita  |e aut 
700 0 1 |a Pósfai Éva  |e aut 
700 0 1 |a Modok Szabolcs  |e aut 
700 0 1 |a Borbényi Zita  |e aut 
700 0 1 |a Forster Tamás  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/13641/1/Nemes_Aortic_stif._u.pdf  |z Dokumentum-elérés