Axotomy Leads to Reduced Calcium Increase and Earlier Termination of CCL2 Release in Spinal Motoneurons with Upregulated Parvalbumin Followed by Decreased Neighboring Microglial Activation.
BACKGROUND: Motoneurons with naturally elevated calcium binding protein content, such as parvalbumin, are more resistant against injury. Furthermore, increase of intracellular calcium, which plays a pivotal role in injury of neurons, could be moderated by elevating their calcium binding proteins....
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
Bentham Science Publishers Ltd.
2017
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| Sorozat: | CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
16 No. 3 |
| doi: | 10.2174/1871527315666161223130409 |
| mtmt: | 3208272 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/13527 |