Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis
Mitochondrial-derived reactive oxygen species have been deemed an important contributor in sepsis pathogenesis. We investigated whether two mitochondria-targeted antioxidants (mtAOX; SkQ1 and MitoTEMPO) improved long-term outcome, lessened inflammation, and improved organ homeostasis in polymicrobia...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
Hindawi Publishing Corporation
2017
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| Sorozat: | OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
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| doi: | 10.1155/2017/6412682 |
| mtmt: | 3274471 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/12972 |