Prognostic impact of macrometastasis linear size in sentinel node biopsy for breast carcinoma
AIM: The aim of the present study was to evaluate the risk of axillary non-sentinel lymph-node metastases (ALN) in breast cancer patients presenting macrometastasis (Mac-m) in the sentinel lymph node (SN). MATERIALS AND METHODS: A retrospective series of 1464 breast cancers from patients who underwe...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
W. B. Saunders
2017
|
| Sorozat: | EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
43 No. 8 |
| doi: | 10.1016/j.ejso.2017.05.007 |
| mtmt: | 3235571 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/12580 |
| LEADER | 02723nab a2200373 i 4500 | ||
|---|---|---|---|
| 001 | publ12580 | ||
| 005 | 20200213104401.0 | ||
| 008 | 171221s2017 hu o 0|| zxx d | ||
| 022 | |a 0748-7983 | ||
| 024 | 7 | |a 10.1016/j.ejso.2017.05.007 |2 doi | |
| 024 | 7 | |a 3235571 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Foschini Maria P. | |
| 245 | 1 | 0 | |a Prognostic impact of macrometastasis linear size in sentinel node biopsy for breast carcinoma |h [elektronikus dokumentum] / |c Foschini Maria P. |
| 260 | |a W. B. Saunders |c 2017 | ||
| 300 | |a 1421-1427 | ||
| 490 | 0 | |a EUROPEAN JOURNAL OF SURGICAL ONCOLOGY |v 43 No. 8 | |
| 520 | 3 | |a AIM: The aim of the present study was to evaluate the risk of axillary non-sentinel lymph-node metastases (ALN) in breast cancer patients presenting macrometastasis (Mac-m) in the sentinel lymph node (SN). MATERIALS AND METHODS: A retrospective series of 1464 breast cancers from patients who underwent ALN dissection following the diagnosis of Mac-m in the sentinel node (SN) was studied. In all the cases the MAC-m linear size was evaluated and correlated with presence or absence of non-SN ALN metastases. RESULTS: Non-SN metastases were detected in 644\1464 cases (43.98%). The risk of further axillary metastases ranged from 20.2% (37/183) in cases with Mac-m between 2 and 2.9 mm, to 65.3% (262/401) in cases with Mac-m measuring > 10 mm. The risk of non-SN ALN metastases showed a 3% increase, parallel to each mm increment in SN metastasis size. The data evaluated with the receiver operating characteristic (ROC) curve showed that the Mac-m could be subdivided according to a new cut-off of 7 mm. pT1 tumours, with Mac-m < 7 mm had a risk of non-SN ALN metastases of <30%. Furthermore 109/127 of these (85.8%) had 3 or less non-SN ALN -metastases. CONCLUSIONS: The present data give a detailed description on the risk of non-SN ALN involvement, that may be useful in the evaluation of breast cancer patients. It is suggested that a Mac-m size of <7 mm is related to a low residual axillary disease burden in breast cancer patients with small (pT1) tumours. | |
| 700 | 0 | 1 | |a Miglio Rossella |e aut |
| 700 | 0 | 1 | |a Quinn Cecily |e aut |
| 700 | 0 | 1 | |a Belgio B |e aut |
| 700 | 0 | 1 | |a Regitnig Peter |e aut |
| 700 | 0 | 1 | |a Bianchi Simonetta |e aut |
| 700 | 0 | 1 | |a Nannini Roberto |e aut |
| 700 | 0 | 1 | |a Buerger Horst |e aut |
| 700 | 0 | 1 | |a Kaya Handan |e aut |
| 700 | 0 | 1 | |a Illyés Ildikó |e aut |
| 700 | 0 | 1 | |a Kulka Janina |e aut |
| 700 | 0 | 1 | |a Wells Clive A. |e aut |
| 700 | 0 | 2 | |a De Gaetano J |e aut |
| 700 | 0 | 2 | |a Lipeniece-Karele I |e aut |
| 700 | 0 | 2 | |a Cserni Gábor |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/12580/1/1_s2.0_S0748798317304857_main_u.pdf |z Dokumentum-elérés |