In vitro antibiotic susceptibility profile of Clostridium difficile excluding PCR ribotype 027 outbreak strain in Hungary

Our study showed the antibiotic susceptibility profile of toxigenic Clostridium difficile isolated from nosocomial and community-acquired CDI between 2008 and 2010. MICs of 200 C. difficile strains were determined using E(R)test method in the case of erythromycin, clindamycin, moxifloxacin, rifampic...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Terhes Gabriella
Maruyama Akiko
Latkóczy Krisztina
Szikra Lenke
Konkoly-Thege Marianne
Princz Gyula
Nagy Erzsébet
Zsoldiné Urbán Edit
Dokumentumtípus: Cikk
Megjelent: 2014
Sorozat:ANAEROBE 30
doi:10.1016/j.anaerobe.2014.08.005

mtmt:2725042
Online Access:http://publicatio.bibl.u-szeged.hu/12083
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520 3 |a Our study showed the antibiotic susceptibility profile of toxigenic Clostridium difficile isolated from nosocomial and community-acquired CDI between 2008 and 2010. MICs of 200 C. difficile strains were determined using E(R)test method in the case of erythromycin, clindamycin, moxifloxacin, rifampicin, and metronidazole. All strains were susceptible to metronidazole in the study period. Resistance rates to erythromycin, clindamycin and moxifloxacin were 31%, 29.5%, and 21.5%, respectively. In the case of rifampicin, the MIC range was quite wide, 11.5% of the tested strains proved to be highly resistant (MIC >/=32 mug/ml) to rifampicin. When we compared these results with our earlier findings from 2006 to 2007, only minor changes in susceptibility over the time-periods could be observed in the case of erythromycin, clindamycin, moxifloxacin, and rifampicin, but metronidazole susceptibility did not show changes. 
700 0 1 |a Maruyama Akiko  |e aut 
700 0 1 |a Latkóczy Krisztina  |e aut 
700 0 1 |a Szikra Lenke  |e aut 
700 0 2 |a Konkoly-Thege Marianne  |e aut 
700 0 2 |a Princz Gyula  |e aut 
700 0 2 |a Nagy Erzsébet  |e aut 
700 0 2 |a Zsoldiné Urbán Edit  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/12083/1/anaeroobe_2014_u.pdf  |z Dokumentum-elérés