Maladaptive mood repair, atypical respiratory sinus arrhythmia, and risk of a recurrent major depressive episode among adolescents with prior major depression

BACKGROUND: Because depressive illness is recurrent, recurrence prevention should be a mainstay for reducing its burden on society. One way to reach this goal is to identify malleable risk factors. The ability to attenuate sadness/dysphoria (mood repair) and parasympathetic nervous system functionin...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kovács Mária
Yaroslavsky Ilya
Rottenberg Jonathan
George Charles
Kiss Enikő
Halas Kitti
Dochnal Roberta
Benák István
Nagyné Baji Ildikó
Vetró Ágnes
Makai Attila
Kapornai Krisztina
Dokumentumtípus: Cikk
Megjelent: 2016
Sorozat:PSYCHOLOGICAL MEDICINE 46 No. 10
doi:10.1017/S003329171600057X

mtmt:3168081
Online Access:http://publicatio.bibl.u-szeged.hu/11846
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245 1 0 |a Maladaptive mood repair, atypical respiratory sinus arrhythmia, and risk of a recurrent major depressive episode among adolescents with prior major depression  |h [elektronikus dokumentum] /  |c  Kovács Mária 
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490 0 |a PSYCHOLOGICAL MEDICINE  |v 46 No. 10 
520 3 |a BACKGROUND: Because depressive illness is recurrent, recurrence prevention should be a mainstay for reducing its burden on society. One way to reach this goal is to identify malleable risk factors. The ability to attenuate sadness/dysphoria (mood repair) and parasympathetic nervous system functioning, indexed as respiratory sinus arrhythmia (RSA), are impaired during depression and after it has remitted. The present study therefore tested the hypothesis that these two constructs also may mirror risk factors for a recurrent major depressive episode (MDE). METHOD: At time 1 (T1), 178 adolescents, whose last MDE had remitted, and their parents, reported on depression and mood repair; youths' RSA at rest and in response to sad mood induction also were assessed. MDE recurrence was monitored until time 2 (T2) up to 2 years later. Mood repair at T1 (modeled as a latent construct), and resting RSA and RSA response to sadness induction (RSA profile), served to predict onset of first recurrent MDE by T2. RESULTS: Consistent with expectations, maladaptive mood repair predicted recurrent MDE, above and beyond T1 depression symptoms. Further, atypical RSA profiles at T1 were associated with high levels of maladaptive mood repair, which, in turn, predicted increased risk of recurrent MDE. Thus, maladaptive mood repair mediated the effects of atypical RSA on risk of MDE recurrence. CONCLUSIONS: This study documented that a combination of behavioral and physiological risk factors predicted MDE recurrence in a previously clinically referred sample of adolescents with depression histories. Because mood repair and RSA are malleable, both could be targeted for modification to reduce the risk of recurrent depression in youths. 
700 0 1 |a Yaroslavsky Ilya  |e aut 
700 0 1 |a Rottenberg Jonathan  |e aut 
700 0 1 |a George Charles  |e aut 
700 0 1 |a Kiss Enikő  |e aut 
700 0 1 |a Halas Kitti  |e aut 
700 0 1 |a Dochnal Roberta  |e aut 
700 0 1 |a Benák István  |e aut 
700 0 2 |a Nagyné Baji Ildikó  |e aut 
700 0 2 |a Vetró Ágnes  |e aut 
700 0 2 |a Makai Attila  |e aut 
700 0 2 |a Kapornai Krisztina  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/11846/1/Kovacs_2016.pdf  |z Dokumentum-elérés