Neuregulin 1-induced AKT and ERK phosphorylation in patients with fragile X syndrome (FXS) and intellectual disability associated with obstetric complications

Neuregulin 1-induced AKT and ERK phosphorylation in patients with fragile X syndrome (FXS) and intellectual disability associated with obstetric complications

Animal models of fragile X syndrome (FXS) suggest the impairment of the intracellular AKT messenger system, which is activated by neuregulin 1 (NRG1), a key regulator of neurodevelopment. We investigated NRG1-induced activation of the AKT and extracellular signal-regulated kinase (ERK) systems by t...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kovács Tamás
Bánsági Boglárka
Kelemen Oguz
Kéri Szabolcs
Dokumentumtípus: Cikk
Megjelent: 2014
Sorozat:JOURNAL OF MOLECULAR NEUROSCIENCE 54 No. 1
doi:10.1007/s12031-014-0257-z

mtmt:2782623
Online Access:http://publicatio.bibl.u-szeged.hu/11362

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