Molecular forms of acetylcholinesterase in the rat extensor digitorum longus and soleus muscles regenerating from notexin-induced necrosis

The activity of acetylcholinesterase molecular forms were examined after separation on sucrose gradients during notexin-induced necrosis and the following regeneration in rat extensor digitorum longus (EDL) and soleus (SOL) muscles. All forms dropped rapidly in both muscles in the first few days aft...

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Elmentve itt :
Bibliográfiai részletek
Szerzők: Kiss Gábor
Zádor Ernő
Szalay Júlia
Somogyi János
Vér Ágota
Dokumentumtípus: Cikk
Megjelent: Chapman and Hall 2004
Sorozat:JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY 25 No. 7
doi:10.1007/s10974-004-2928-9

mtmt:1668066
Online Access:http://publicatio.bibl.u-szeged.hu/10889
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520 3 |a The activity of acetylcholinesterase molecular forms were examined after separation on sucrose gradients during notexin-induced necrosis and the following regeneration in rat extensor digitorum longus (EDL) and soleus (SOL) muscles. All forms dropped rapidly in both muscles in the first few days after single notexin injection. After a delay small globular forms (G1+G2) started to regenerate from day 7 and larger forms (G4 and A12) from day 10 in EDL. The A8 form which cannot be detected in normal EDL was present between day 7 and day 28. In SOL the recovery of AChE forms begun already on day 3. The small globular forms displayed a more rapid increase between day 3 and day 7 then the other forms. In SOL we observed a temporary overshooting peak at day 7 in the activity of all molecular forms. Both muscles recovered their normal AChE pattern by that time when muscle fibres regained their normal diameter (day 28). Most of the events of regeneration of AChE forms resembled those of normal myogenesis. © 2005 Springer. 
700 0 1 |a Zádor Ernő  |e aut 
700 0 1 |a Szalay Júlia  |e aut 
700 0 1 |a Somogyi János  |e aut 
700 0 1 |a Vér Ágota  |e aut 
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