Fluorimetric Methods for Analysis of Permeability, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter
The cell membrane P-glycoprotein (P-gp; MDR1, ABCB1) is an energy-dependent efflux pump that belongs to the ATP-binding cassette (ABC) family of transporters, and has been associated with drug resistance in eukaryotic cells. Multidrug resistance (MDR) is related to an increased expression and functi...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Könyv része |
| Megjelent: |
Springer New York
New York
2016
|
| Sorozat: | Methods in Molecular Biology
1395 METHODS IN MOLECULAR BIOLOGY 1395 Cancer Drug Resistance : Overviews and Methods 1395 |
| doi: | 10.1007/978-1-4939-3347-1_7 |
| mtmt: | 3026841 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10420 |