Efficient synthesis of 3,4-and4,5-dihydroxy-2-amino-cyclohexanecarboxylic acid enantiomers
An efficient method for the synthesis of (1S,2R,4R,5S)- and (1R,2R,4R,5S)-2-amino-4,5-dihydroxycyclohexanecarboxylic acids (-)-6 and (-)-9 and (1R,2R,3S,4R)- and (1S,2R,3S,4R)-2-amino- 3,4-dihydroxycyclohexanecarboxylic acids (-)-15 and (-)-18 was developed by using the OsO4-catalyzed oxidation o...
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2009
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| Sorozat: | TETRAHEDRON-ASYMMETRY
20 No. 19 |
| doi: | 10.1016/j.tetasy.2009.09.001 |
| mtmt: | 1286919 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10393 |
| LEADER | 01487nab a2200265 i 4500 | ||
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| 005 | 20190524133606.0 | ||
| 008 | 170201s2009 hu o 0|| zxx d | ||
| 022 | |a 0957-4166 | ||
| 024 | 7 | |a 10.1016/j.tetasy.2009.09.001 |2 doi | |
| 024 | 7 | |a 1286919 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Benedek Gabriella | |
| 245 | 1 | 0 | |a Efficient synthesis of 3,4-and4,5-dihydroxy-2-amino-cyclohexanecarboxylic acid enantiomers |h [elektronikus dokumentum] / |c Benedek Gabriella |
| 260 | |c 2009 | ||
| 300 | |a 2220-2225 | ||
| 490 | 0 | |a TETRAHEDRON-ASYMMETRY |v 20 No. 19 | |
| 520 | 3 | |a An efficient method for the synthesis of (1S,2R,4R,5S)- and (1R,2R,4R,5S)-2-amino-4,5-dihydroxycyclohexanecarboxylic acids (-)-6 and (-)-9 and (1R,2R,3S,4R)- and (1S,2R,3S,4R)-2-amino- 3,4-dihydroxycyclohexanecarboxylic acids (-)-15 and (-)-18 was developed by using the OsO4-catalyzed oxidation of Boc-protected (1S,2R)-2-aminocyclohex-4-enecarboxylic acid (+)-2 and (1R,2S)-2-aminocyclohex-3-ene-carboxylic acid (+)-11. Good yields were obtained. The stereochemistry of the synthesized compounds was proven by NMR spectroscopy. (C) 2009 Elsevier Ltd. All rights reserved. | |
| 700 | 0 | 1 | |a Palkó Márta |e aut |
| 700 | 0 | 1 | |a Wéber Edit |e aut |
| 700 | 0 | 1 | |a Martinek Tamás A. |e aut |
| 700 | 0 | 1 | |a Forró Enikő |e aut |
| 700 | 0 | 1 | |a Fülöp Ferenc |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/10393/1/1_s2.0_S0957416609006855_main_u.pdf |z Dokumentum-elérés |