Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi
Studies of gene function in the mouse have relied mainly on gene targeting via homologous recombination. However, this approach is difficult to apply in specific windows of time, and to simultaneously knock-down multiple genes. Here we report an efficient method for dsRNA-mediated gene silencing in...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2005
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| Sorozat: | BMC Developmental Biology
5 No. 1 |
| doi: | 10.1186/1471-213X-5-28 |
| mtmt: | 1920815 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10214 |
| LEADER | 01536nab a2200325 i 4500 | ||
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| 005 | 20190522142245.0 | ||
| 008 | 170109s2005 hu o 0|| zxx d | ||
| 022 | |a 1471-213X | ||
| 024 | 7 | |a 10.1186/1471-213X-5-28 |2 doi | |
| 024 | 7 | |a 1920815 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Soares Miguel L. | |
| 245 | 1 | 0 | |a Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi |h [elektronikus dokumentum] / |c Soares Miguel L. |
| 260 | |c 2005 | ||
| 300 | |a Terjedelem: 11 p.-Azonosító: 28 | ||
| 490 | 0 | |a BMC Developmental Biology |v 5 No. 1 | |
| 520 | 3 | |a Studies of gene function in the mouse have relied mainly on gene targeting via homologous recombination. However, this approach is difficult to apply in specific windows of time, and to simultaneously knock-down multiple genes. Here we report an efficient method for dsRNA-mediated gene silencing in late cleavage-stage mouse embryos that permits examination of phenotypes at post-implantation stages. | |
| 700 | 0 | 1 | |a Haraguchi Seiki |e aut |
| 700 | 0 | 2 | |a Torres-Padilla Maria-Elena |e aut |
| 700 | 0 | 2 | |a Kalmár Tibor |e aut |
| 700 | 0 | 2 | |a Carpenter Lee |e aut |
| 700 | 0 | 2 | |a Bell Graham |e aut |
| 700 | 0 | 2 | |a Morrison Alastair |e aut |
| 700 | 0 | 2 | |a Ring Christopher JA |e aut |
| 700 | 0 | 2 | |a Clarke Neil J. |e aut |
| 700 | 0 | 2 | |a Glover David M. |e aut |
| 700 | 0 | 2 | |a Zernicka-Goetz Magdalena |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/10214/1/Soares%20et%20al%202005.pdf |z Dokumentum-elérés |