Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study
The kynurenine pathway converts tryptophan into various compounds, including L-kynurenine, which in turn can be converted to the excitatory amino acid receptor antagonist kynurenic acid, which may therefore serve as a protective agent in such neurological disorders as epileptic seizures. Kynurenic a...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
Pergamon Press
2004
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| Sorozat: | NEUROPHARMACOLOGY
47 No. 6 |
| doi: | 10.1016/j.neuropharm.2004.06.007 |
| mtmt: | 1030160 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10117 |