Coordinated protein and DNA remodeling by human HLTF and comparison of its activity with Bloom Syndrome helicase protein
Human HLTF (Helicase Like Transcription Factor) is a member of the Swi2/Snf2 family of ATP-driven molecular motor proteins. Like many members of Swi2/Snf2 family, HLTF does not exhibit a canonical DNA helicase activity but has an ATP hydrolysis-driven double stranded (ds) DNA translocase activity. T...
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| Dokumentumtípus: | Disszertáció |
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2011-12-09
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| doi: | 10.14232/phd.1089 |
| mtmt: | 2774037 |
| Online Access: | http://doktori.ek.szte.hu/1089 |