The role of intracellular Ca2+signaling in the exocrine pancreatic damage during acute pancreatitis
Acute biliary pancreatitis poses a significant clinical challenge as currently no specific pharmaceutical treatment exists. Disturbed intracellular Ca2+ signalling caused by bile acids is a hallmark of the disease, which induces increased reactive oxygen species (ROS) production, mitochondrial damag...
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| További közreműködők: | |
| Dokumentumtípus: | Disszertáció |
| Megjelent: |
2020-06-30
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| Kulcsszavak: | acinar cell necrosis, acute pancreatitis, bile acid, Ca2+ signalling, epithelial ion transport, TRPM2 channel |
| Tárgyszavak: | |
| doi: | 10.14232/phd.10488 |
| mtmt: | 31933101 |
| Online Access: | http://doktori.ek.szte.hu/10488 |