Investigation of the transformation of 5-fluorouracil cytostatics by UV and VUV photolysis
In this work, UV (254 nm), UV/VUV185 nm, and VUV172 nm photolysis of 5-fluorouracil (5- FLU), a cytostatic drug were investigated. For the water treatments three type of lightsources were applied: a low-pressure mercury vapour lamps emitting only 254 nm UV light, an other low-pressure mercury vapour...
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| Dokumentumtípus: | Könyv része |
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2020
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
26 |
| Kulcsszavak: | Analitikai kémia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/74043 |
| LEADER | 01908naa a2200253 i 4500 | ||
|---|---|---|---|
| 001 | acta74043 | ||
| 005 | 20220808153920.0 | ||
| 008 | 211118s2020 hu o 1|| eng d | ||
| 020 | |a 978-963-306-771-0 | ||
| 040 | |a SZTE Egyetemi Kiadványok Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Dercze Dávid | |
| 245 | 1 | 0 | |a Investigation of the transformation of 5-fluorouracil cytostatics by UV and VUV photolysis |h [elektronikus dokumentum] / |c Dercze Dávid |
| 260 | |c 2020 | ||
| 300 | |a 379-383 | ||
| 490 | 0 | |a Proceedings of the International Symposium on Analytical and Environmental Problems |v 26 | |
| 520 | 3 | |a In this work, UV (254 nm), UV/VUV185 nm, and VUV172 nm photolysis of 5-fluorouracil (5- FLU), a cytostatic drug were investigated. For the water treatments three type of lightsources were applied: a low-pressure mercury vapour lamps emitting only 254 nm UV light, an other low-pressure mercury vapour lamps emitting both 254 nm UV and 185 nm VUV light, and a Xe excimer light source emitting 172 nm VUV photons. In parallel, with the transformation of 5-FLU, H2O2 formation was detected and measured. During UV/VUV185 nm photolysis, the formation of H2O2 follows a maximum curve, while in the case of UV photolysis, it shows a saturation curve. Its concentration reached higher value in the case of UV/VUV185 nm than in UV radiation. To enhance the efficiency of the reactors, we used air, O2 and N2 gases and assessed their effect to the photolysis of 5-FLU to see wich parameters are the most suitable for transforming it. | |
| 650 | 4 | |a Természettudományok | |
| 650 | 4 | |a Kémiai tudományok | |
| 695 | |a Analitikai kémia | ||
| 700 | 0 | 1 | |a Farkas Luca |e aut |
| 700 | 0 | 1 | |a Alapi Tünde |e aut |
| 710 | |a International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged) | ||
| 856 | 4 | 0 | |u http://acta.bibl.u-szeged.hu/74043/1/proceedings_of_isaep_2020_379-383.pdf |z Dokumentum-elérés |