Microwave-assisted Pd-catalyzed C-P or C-C cross couplings on 13α-estrane core
Novel 2- or 4-substituted 13α-estrone derivatives were synthesized via Hirao or Suzuki reaction. Transformations of 2- and/or 4-halogenated derivatives of 13α-estrone and its 3- benzyl or -methyl ether were carried out in a microwave (MW) reactor. Facile and efficient CC or C-P coupling procedures w...
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| Dokumentumtípus: | Könyv része |
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2018
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
24 |
| Kulcsszavak: | Szerves kémia |
| Online Access: | http://acta.bibl.u-szeged.hu/56354 |
| Tartalmi kivonat: | Novel 2- or 4-substituted 13α-estrone derivatives were synthesized via Hirao or Suzuki reaction. Transformations of 2- and/or 4-halogenated derivatives of 13α-estrone and its 3- benzyl or -methyl ether were carried out in a microwave (MW) reactor. Facile and efficient CC or C-P coupling procedures were established using Pd or Ni catalysts. The newly synthesized compounds might have promising antitumoral properties. |
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| Terjedelem/Fizikai jellemzők: | 296-298 |
| ISBN: | 978-963-306-623-2 |