01832naa a2200229 i 4500 acta56249 20260224081030.0 190103s2017 hu o 100 hun d 978-963-306-563-1 SZTE Egyetemi Kiadványok Repozitórium hun hun Körmöczi Tímea Analysis of new synthetic cannabinoid in human urine by LC-MS/MS [elektronikus dokumentum] / Körmöczi Tímea 2017 457-462 Proceedings of the International Symposium on Analytical and Environmental Problems 23 Synthetic cannabinoids (SCs) are a group of novel psychoactive substances, which bind to cannabinoid receptors (CB1 and CB2). One of the largest groups of SCs are smoking mixtures, which are intended as legal replacements of cannabis and distributed on the illicit drug market. In 2016, 11 new SCs were reported by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). The most commonly used techniques for quantitation of SCs in urine are high performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). In this study we analysed in 2016-2017 released 6 new SCs such as 5F-MN18, AMB-CHMINACA, AMB-FUBINACA, APP-CHMINACA, CUMYL-4CNBINACA and THJ-2201. The LC-MS/MS system was optimised and the mass of identified parent ions, daughter ions and related retention time were determined. Matrix effect, extraction recovery and process efficiency were evaluated by the method proposed by Matuszewski et al. Analitikai kémia Sija Éva aut Berkecz Róbert aut International Symposium on Analytical and Environmental Problems (23.) (2017) (Szeged) http://acta.bibl.u-szeged.hu/56249/1/proceedings_of_isaep_2017_457-462.pdf Dokumentum-elérés