Analysis of new synthetic cannabinoid in human urine by LC-MS/MS

Synthetic cannabinoids (SCs) are a group of novel psychoactive substances, which bind to cannabinoid receptors (CB1 and CB2). One of the largest groups of SCs are smoking mixtures, which are intended as legal replacements of cannabis and distributed on the illicit drug market. In 2016, 11 new SCs we...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Körmöczi Tímea
Sija Éva
Berkecz Róbert
Testületi szerző: International Symposium on Analytical and Environmental Problems (23.) (2017) (Szeged)
Dokumentumtípus: Könyv része
Megjelent: 2017
Sorozat:Proceedings of the International Symposium on Analytical and Environmental Problems 23
Kulcsszavak:Analitikai kémia
Online Access:http://acta.bibl.u-szeged.hu/56249
LEADER 01832naa a2200229 i 4500
001 acta56249
005 20220808154939.0
008 190103s2017 hu o 1|| zxx d
020 |a 978-963-306-563-1 
040 |a SZTE Egyetemi Kiadványok Repozitórium  |b hun 
041 |a zxx 
100 1 |a Körmöczi Tímea 
245 1 0 |a Analysis of new synthetic cannabinoid in human urine by LC-MS/MS  |h [elektronikus dokumentum] /  |c  Körmöczi Tímea 
260 |c 2017 
300 |a 457-462 
490 0 |a Proceedings of the International Symposium on Analytical and Environmental Problems  |v 23 
520 3 |a Synthetic cannabinoids (SCs) are a group of novel psychoactive substances, which bind to cannabinoid receptors (CB1 and CB2). One of the largest groups of SCs are smoking mixtures, which are intended as legal replacements of cannabis and distributed on the illicit drug market. In 2016, 11 new SCs were reported by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). The most commonly used techniques for quantitation of SCs in urine are high performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). In this study we analysed in 2016-2017 released 6 new SCs such as 5F-MN18, AMB-CHMINACA, AMB-FUBINACA, APP-CHMINACA, CUMYL-4CNBINACA and THJ-2201. The LC-MS/MS system was optimised and the mass of identified parent ions, daughter ions and related retention time were determined. Matrix effect, extraction recovery and process efficiency were evaluated by the method proposed by Matuszewski et al. 
695 |a Analitikai kémia 
700 0 1 |a Sija Éva  |e aut 
700 0 1 |a Berkecz Róbert  |e aut 
710 |a International Symposium on Analytical and Environmental Problems (23.) (2017) (Szeged) 
856 4 0 |u http://acta.bibl.u-szeged.hu/56249/1/proceedings_of_isaep_2017_457-462.pdf  |z Dokumentum-elérés