Enantioseparation of amino alcohol analogs possessing 1,2,3,4-tetrahydroisoquinoline skeleton and its derivatives using polysaccharide-based chiral stationary phases
The stereoisomers of 1,2,3,4-tetrahydroisoquinoline amino alcohol analogues were directly separated on modified cellulose based chiral stationary phases. The effects of the mobile phase composition, the structure of the analytes and temperature on the separations were investigated. Experiments were...
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| Dokumentumtípus: | Könyv része |
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2015
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
21 |
| Kulcsszavak: | Analitikai kémia |
| Online Access: | http://acta.bibl.u-szeged.hu/56002 |
| Tartalmi kivonat: | The stereoisomers of 1,2,3,4-tetrahydroisoquinoline amino alcohol analogues were directly separated on modified cellulose based chiral stationary phases. The effects of the mobile phase composition, the structure of the analytes and temperature on the separations were investigated. Experiments were performed at constant mobile phase compositions with varying temperature in order to calculate thermodynamic parameters from plots of ln α versus 1/T. Some mechanistic aspects of the chiral recognition process are discussed with respect to the structures of the analytes. |
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| Terjedelem/Fizikai jellemzők: | 359-363 |
| ISBN: | 978-963-306-411-5 |