Environmental monitoring of glyphosate and assessment of its combined cytotoxicity with adjuvants

Pesticide toxicology currently focuses mainly on two areas: long-term effects of given compounds and cocktail effects of chemicals, including combined effects of pesticide active ingredients with their adjuvants, as seen in the case of glyphosate-based herbicides. In this study surface water polluti...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Ottucsák Marianna
Klátyik Szandra
Gyurcsó Gergő
Mörtl Mária
Darvas Béla
Székács András
Testületi szerző: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Dokumentumtípus: Könyv része
Megjelent: 2015
Sorozat:Proceedings of the International Symposium on Analytical and Environmental Problems 21
Kulcsszavak:Kémia, Biokémia, Peszticid, Toxikológia
Online Access:http://acta.bibl.u-szeged.hu/55929
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520 3 |a Pesticide toxicology currently focuses mainly on two areas: long-term effects of given compounds and cocktail effects of chemicals, including combined effects of pesticide active ingredients with their adjuvants, as seen in the case of glyphosate-based herbicides. In this study surface water pollution in an agricultural region of Hungary by glyphosate was determined by ELISA method, and cytotoxic effects on HEK293 and NE-4C cells by glyphosate, its formulated herbicide (ROUNDUP® ) and adjuvant (polyethoxylated tallowamine, POEA) were compared. ROUNDUP and POEA were found to be equitoxic at short exposures (LC50: 10-15 ng/ml in 6 hrs), while glyphosate occurred to be of 500-750-fold less toxicity. 
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