01955nab a2200217 i 4500 acta32949 20260519094330.0 161017s2013 hu o 000 eng d 1588-385X SZTE Egyetemi Kiadványok Repozitórium hun eng Zanzen Ulrike Antibacterial action of copperions on food-contaminating bacteria [elektronikus dokumentum] / Zanzen Ulrike University of Szeged Szeged 2013 149-151 Acta biologica Szegediensis 57 No. 2 Silver and copper ions are widely used as antibacterial agents but the basic molecular mechanism of this effect is still poorly understood. The analysis of our investigation gives clear indications that Ag+ do react with the bacterial cells and do not stay as silver in the system. Significant lower silver cysteine content coupled with higher silver histidine content in Gram-positive cells indicate that the peptidoglycan multi-layer could be buffering the biocidal effect of silver for the Gram-positives at least in part. Interaction with DNA or proteins can occur through Ag-N bonding. The formation of silver cysteine can be confirmed for both bacterial cell types which thus supports the hypothesis that enzyme catalyzed reactions and the electron transport chain within the cell is disrupted. The antibacterial property of copper is attributed mainly to adhesion with bacteria because of their opposite electrical charges, resulting in a reduction reaction at the bacterial cell wall. Nanoparticles with a larger surface-to-volume ratio might provide more efficient means for antibacterial activity. First results suggest that copper ions do not react compared to silver ions. Természettudományok Biológiai tudományok Élelmiszerbiztonság, Mikrobiológia - alkalmazott http://acta.bibl.u-szeged.hu/32949/1/57149.pdf Dokumentum-elérés